Spatiotemporal Structure in Large Neuronal Networks Detected from Cross-Correlation

Spatiotemporal Kriging with External Drift

In statistics it is often assumed that sample observations are independent. But sometimes in practice, observations are somehow dependent on each other. Spatiotemporal data are dependent data which their correlation is due to their spatiotemporal locations.Spatiotemporal models arise whenever data are collected across bothtime and space. Therefore such models have to be analyzed in termsof thei...

Emergence of Preferred Firing Sequences in Large Spiking Neural Networks during Simulated Neuronal Development

Two main processes concurrently refine the nervous system over the course of development: cell death and selective synaptic pruning. We simulated large spiking neural networks (100 x 100 neurons "at birth") characterized by an early developmental phase with cell death due to excessive firing rate, followed by the onset of spike timing dependent synaptic plasticity (STDP), driven by spatiotempor...

New Insight from Using Spatiotemporal Image Correlation in Prenatal Screening of Fetal Conotruncal Defects

Adaptive functional modeling of neural activity: a reservoir computing approach to neuronal cultures

Biological neural networks (BNN) are very rich and complex in terms of structure and spatiotemporal activity patterns. This complexity does not allow to directly relate their anatomical and biophysical properties to the dynamics of their electrical activity. Functional relevance of their structure and dynamics is also difficult to track analytically. The focus of this thesis is the development ...

Transient neuronal coactivations embedded in globally propagating waves underlie resting-state functional connectivity.

Resting-state functional connectivity (FC), which measures the correlation of spontaneous hemodynamic signals (HemoS) between brain areas, is widely used to study brain networks noninvasively. It is commonly assumed that spatial patterns of HemoS-based FC (Hemo-FC) reflect large-scale dynamics of underlying neuronal activity. To date, studies of spontaneous neuronal activity cataloged heterogen...